Women with ≥2 UTIs in 6 months or ≥3 in 12 months, under clinician guidance.
Form: extract
Dose: 36 mg PAC-A/day (or equivalent per product)
once daily with water
6–12 months, then reassess
Why: Cochrane 2023 shows significant reduction in recurrences; AUA conditionally recommends in rUTI.
Dose: ≥1×10^9 CFU/day orally and/or intravaginally for 6 months