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Premenstrual syndrome (PMS) – symptom relief

Menstruating individuals with PMS after other causes ruled out.

women

hormonal

Reduce somatic and mood symptoms

Improve function in the luteal phase

Core stack

Chaste tree berry (Vitex agnus-castus, standardized extract)

Form: standardized extract (e.g., Ze 440)

Dose: 20–40 mg/day for 3 cycles

daily

at least 3 cycles, then reassess

Why: RCTs (incl. BMJ) and reviews show reduction of PMS symptoms vs placebo.

Cautions

Sources

Vitamin B6 (pyridoxine)

Form: tablets

Dose: 50–100 mg/day in the luteal phase or daily (short-term)

with food

2–3 cycles, then pause and reassess

Why: Older meta-analyses suggest moderate benefit, but overall evidence quality is limited.

Cautions

Sources

Complex herbal blends with undocumented composition: Lack of quality RCTs; variable product quality.