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Gut Resilience During Antibiotics (AAD prevention)

Adults/kids using systemic antibiotics (consult pediatrician for children).

gut

antibiotics

probiotics

reduce risk of antibiotic-associated diarrhea (AAD)

Core stack

Saccharomyces boulardii CNCM I-745

Dose: 250–500 mg twice daily (or 5–10 billion CFU/day)

Start within 24 h of first antibiotic dose; continue through course and 3–7 days after

Antibiotic course + short tail

Why: Consistent evidence for reducing AAD risk in adults and children.

Cautions

Sources

Lactobacillus rhamnosus GG (ATCC 53103)

A (pediatrics), B (adults)

Dose: 10–20 billion CFU/day

Separate from antibiotics by ≥2–3 h

Antibiotic course + 3–7 days

Why: Reduces risk/duration of AAD in multiple trials.

Sources

Unspecified ‘multi-strain’ probiotics without documented strains/doses: Strain-specific effects; lack of evidence for generic blends.